QT corrected and QTc dispersion across different phases of menstrual cycle- A cross-sectional study

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Original Article

Author Details : Nirmala S. Anand*, Shivaprasad S. Goudar

Volume : 5, Issue : 4, Year : 2018

Article Page : 478-482

https://doi.org/10.18231/2394-2126.2018.0111

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Abstract

Introduction: The gonadal hormones accompanying the menstrual cycle in a female affect the ventricular repolarization regionally in the cardiac muscle as well as affects its recovery time both of which are QT_c AND QT_d measured conventionally using a non-invasive ECG. A prolonged QT_c and QT_d are predictors of cardiac morbidity and mortality.
Aim: The aim of the present study was to examine whether the cardiac ventricular repolarization is altered during different phases of menstrual cycle by the endogenous gonadal hormones.
Materials and Methods: Thirty eumenorrhic females were examined using 12 lead ECG during the follicular and luteal phases of menstrual cycle.
Statistical Analysis: Data was analysed statistically using student’s paired t-test.
Results: It was observed that the heart rate in follicular phase was (78.8 ±7.48) while in luteal (84 ± 8.17), R-R interval in follicular was (82±5.89) while in luteal phase was (77±3.69) QT interval in follicular was (0.39±0.09) while in luteal phase was (0.33±0.08), QT_c in follicular was (0.43±0.03) while in luteal phase was (0.39±0.03), QT_d in follicular was (67 ± 2.30) while in luteal phase was (58±4.08).
Conclusion: We hence elucidate interactions between the sex steroids and cardiac conduction dynamics which is characterized by a prolonged QT_c and QT_d during the follicular phase.

Keywords: Endogenous, Gonadal, Menstrual cycle, Repolarization

How to cite : Anand N S, Goudar S S, QT corrected and QTc dispersion across different phases of menstrual cycle- A cross-sectional study. Indian J Clin Anat Physiol 2018;5(4):478-482

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