Visual evoked potential changes in pre-diabetics, type 2 diabetics and normal subjects

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Original Article

Author Details : Zaahid Naseer, Arun Kumar M, Roopakala M S, Pramila Kalra

Volume : 5, Issue : 3, Year : 2018

Article Page : 326-330

https://doi.org/10.18231/2394-2126.2018.0075

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Abstract

Introduction: Diabetes mellitus type 2 is the most common metabolic disorder and diabetic retinopathy is the leading cause of blindness. Persistent hyperglycemia leads to damage of microvasculature supplying the retina and optic pathway. Visual evoked potential is the most commonly used test to evaluate the integrity of visual pathway. The purpose of the study is to compare the visual evoked potential latency and amplitude between the pre-diabetes, diabetes and normal controls.
Materials and Methods: There were three groups in the study with 23 patients in each group; pre-diabetic group, diabetic group and controls. Group was made based on fasting blood sugar levels. Pattern visual evoked potential was measured in all the groups by connecting scalp electrodes according to 10-20 International electrode placement system. Latency and amplitude of N75, P100 and N145 were measured and used for statistical analysis.
Results: All the parameters individually were compared between three groups using ANOVA test. There was no statistical difference between latencies and amplitude all the three parameters N75, P100, N145 in all the three channels O1-NE, O2- NE, Oz-NE in all the three groups.
Conclusion: There is no differences in the visual evoked potential latency and amplitude in the between pre-diabetics, diabetes and controls.

Keywords: Visual evoked Potential, Diabetic retinopathy, Pre-diabetes, P100, N75, N145.

How to cite : Naseer Z, Arun Kumar M, Roopakala M S, Kalra P, Visual evoked potential changes in pre-diabetics, type 2 diabetics and normal subjects. Indian J Clin Anat Physiol 2018;5(3):326-330

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