Retrospective observational study of antimicrobial drugs utilization in medical ICU in a tertiary care teaching hospital of Himachal Pradesh

---

Original Article

Author Details : Arvind Kumar, Dinesh Kansal, Usha Kumari Chaudhary

Volume : 2, Issue : 3, Year : 2017

Article Page : 93-98

Suggest article by email

Get Permission

---

Abstract

Introduction: Patients admitted in Intensive Care Units (ICUs) are already sick and they are vulnerable to superadded infections. They suffer from other co-morbidities and also undergo invasive procedures. So these patients are under cover of antimicrobial drugs.
Materials and Method: It was a retrospective observational study, conducted during a period from March, 2016 to July, 2016. Data of 152 patients was collected from the Central Record Section of the hospital. Drug utilization pattern of antimicrobial agents was analyzed.
Results: Out of 152 patients, 100 (65%) were males and 52 (35%) were females. The mean age was 60.05 ± 16.05 years with a range of 20 - 90 years. The mean age of males was 58.72 ± 14.85 years and females were 62.52 ± 17.80 years. Average duration of hospital stay was 2.96 ± 2.57 days with a range of 1 to 20 days. Total of 131 antibiotics were prescribed. Antibiotics prescribed were 3^rd generation cephalosporins in 43 patients, macrolides in 27 patients, quinolones in 9, antianaerobics in 8, tetracycline in 5, oxazolidinones, aminoglycosides, antifungals and others in 2 patients each. FDCs were prescribed in 24% prescriptions. Prescription pattern of FDCs was piperacillin + tazobactam in 20 patients, amoxicillin + clavulanic acid in 5 patients, ceftriaxone + sulbactam in 3 patients, polymyxin B + bacitracin + neomycin in 2 patients and ofloxacin + ornidazole in 1 patient.
Conclusion: Drug utilization studies provide us prescription pattern in the medical ICU. We can minimize the incidence of antimicrobial resistance by following the standard guidelines of antimicrobial prescription.

Keywords: Drug utilization, Antimicrobials, ICU

How to cite : Kumar A, Kansal D, Chaudhary U K, Retrospective observational study of antimicrobial drugs utilization in medical ICU in a tertiary care teaching hospital of Himachal Pradesh. Indian J Clin Anat Physiol 2017;2(3):93-98

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.