Examination of vitamin D status in individuals with obsessive-compulsive disorder

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Original Article

Author Details : Tshetiz Dahal*, Jeby Abraham

Volume : 11, Issue : 3, Year : 2024

Article Page : 164-169

https://doi.org/10.18231/j.ijcap.2024.035

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Abstract

Context: It is uncertain how vitamin D affects obsessive-compulsive disorder (OCD).
Aim: Research indicates that neuropsychiatric disorders may be linked to vitamin D insufficiency. This study aims to look into vitamin D levels in people with OCD diagnoses. Furthermore, the relationship between the severity of OCD symptoms and serum vitamin D levels is examined.
Materials and Methods: The study included 170 healthy volunteers and approximately 174 newly diagnosed OCD patients. To evaluate the intensity of OCD symptoms, the Yale–Brown Obsessive Compulsive Scale (YBOCS) was employed. The two groups' serum vitamin D levels were contrasted.
Results: It was discovered that the OCD group's serum vitamin D levels were noticeably lower than those of the control group. There was no association found between the length of disease in OCD patients and blood vitamin D levels, but there was a negative correlation between the serum vitamin D levels and the overall scale scores, obsession, and compulsion as measured by YBOCS.
Conclusions: To the best of our knowledge, this is one of the first studies looking at vitamin D levels in adult OCD patients who have just received a diagnosis and do not have any concomitant conditions. Even though our results imply that vitamin D might be involved in the pathogenesis of OCD, more research is required to corroborate our findings.
 

Keywords: Biomarkers, Central nervous system, Obsessive­ compulsive disorder, Vitamin D.

How to cite : Dahal T, Abraham J, Examination of vitamin D status in individuals with obsessive-compulsive disorder. Indian J Clin Anat Physiol 2024;11(3):164-169

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