Association of blood uric acid with the duration of diabetes in type 2 diabetics: A pilot study

---

Original Article

Author Details : Chandini K, G Manogna, Mohammed Jaffer Pinjar*

Volume : 7, Issue : 4, Year : 2020

Article Page : 334-337

https://doi.org/10.18231/j.ijcap.2020.070

Suggest article by email

Get Permission

---

Abstract

Diabetes Mellitus is the most common non-communicable disease which is vastly conquering both the developed & developing countries of the world. Hypothesis: serum uric acid plays as an independent risk factor for the development of type 2 diabetes. Studies revealing the clearance of uric acid reduced with insulin resistance are few in numbers. A positive correlation between uric acid and glucose levels leads to the development of type 2 diabetes.
Objective: To correlate the levels of blood uric acid with the duration of diabetes in type 2 diabetics.
Materials and Methods: Fifteen type 2 diabetes patients with no history of any complications and other systemic organ & metabolic disorders like gout & obesity randomly selected for this cross-sectional study. A biochemical investigation, like the Uricase method employed for fasting serum uric acid levels estimation. Statistical analysis by the Pearson correlation test used.
Results: Positive correlation of serum uric acid with the duration of diabetes in type 2 diabetic patients found to be statistically significant (r = +0.6, p < 0> Conclusion: The positive association of fasting serum uric acid with the duration of type 2 diabetes suggests that uric acid acts as an independent biochemical marker for prognosis of the type 2 diabetes.
Drugs that reduce the uric acid levels may be useful in avoiding the development and prognosis of insulin resistance that causes type 2 diabetes and other complications.

Keywords: Insulin resistance, Uricase method.

How to cite : Chandini K, Manogna G , Pinjar M J, Association of blood uric acid with the duration of diabetes in type 2 diabetics: A pilot study. Indian J Clin Anat Physiol 2020;7(4):334-337

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.